The ground vibration generated by human activities such as traffic load, machine operation, explosion and engineering construction will inevitably lead to environmental vibration pollution. To solve the problem, a new vibration isolation material with excellent damping capacity, Duxseal, is put forward for active vibration isolation in this paper. Based on two dimensional semi-analytical boundary element method, the calculation program is compiled to calculate the ground horizontal displacement amplitude, vertical displacement amplitude and amplitude attenuation coefficient with different width, thickness and embedment depth of Duxseal in half-space homogeneous elastic foundation. In addition, the influence of Duxseal width, thickness and embedment depth on ground displacement is analyzed, and the vibration isolation between Duxseal and WIB is compared comprehensively. The results indicate that Duxseal is an effective material to reduce the ground displacement amplitude under vertical excitation condition as active vibration isolation barrier. Unlike WIB active vibration isolation, Duxseal material can achieve the ideal vibration isolation effect only with reasonable width, thickness and relatively bigger embedment depth. The increase of the width, thickness and embedment depth of Duxseal material within a certain range can increase effectiveness of isolation for ground vibration. In addition, the isolation effect of Duxseal material is also proved by field test.