With regard to the numerous analytical methods corresponding to different segments in the theoretical framework of the wind effect analysis of large-span roofs，which are also not well coordinated or unified，a practical method is proposed to analyze the multi-target equivalent static wind loads considering the characteristics of wind-vibration responses. Based on the combination of the pulsating wind-induced background response，resonant response and their coupling term，the load response correlation（LRC） theory is applied to derive the fundamental load vectors of the multi-target equivalent equations，in order to fully coordinate the pulsating wind-vibration response and reconstruct the wind-vibration responses. On this basis，the multi-target equivalent static wind load can be obtained by solving the multi-target equivalent equations using the least square method. Introducing the concept of strain energy，and considering all nodal responses and the contribution of the three components of the strain energy of each nodal response to the total response，the contribution coefficient of the response component is therefore defined to determine the characteristic category of the pulsating wind-induced response of the large-span roof. Based on this，the multi-target equivalent equations are constructed accurately and solved efficiently. Taking the roof of Beijing Olympic Park Tennis Center Stadium as an example，the type of the wind-vibration responses is identified. Hence，the multi-target equivalent static wind loads and the static responses are calculated and then compared with the target responses in the frequency domain The results indicate that the presented method can accurately and efficiently compute the multi-target equivalent static wind loads of structures，with valuable engineering applications.