To confine the vibration energy of a periodically framed cylindrical shell in the pass bands，irregular stiffener size configuration can be used as a control measure. An investigation on localization of a framed cylindrical shell with irregular stiffener size configuration is presented. The vibration of the cylindrical shell is equivalent as a coupled oscillator chain system. Using the vibration results acquired by finite element method as input，resonance frequency parameter and coupling parameter of the equivalent oscillator chain can be acquired by identification technology combined with wave number analysis. Then the localization factor of the disorder configuration model，which is the quantification of localization，can be predicted using the formula derived for the coupled oscillator chain system. The irregular configuration stiffener size parameter can be acquired using reference model identification technology. Analysis of the framed cylindrical shells with irregular stiffener size configuration shows that，vibration can be confined to the source due to the element ground stiffness irregularity. The degree of localization is related to vibration mode，irregularity configuration parameter and frequency parameter.