Offshore wind turbine is a technological commanding height in wind power industrial development in future and it faces more complicated extreme wind environments compared with onshore wind turbine. To disclose wind load distribution characteristics of wind turbine under typhoon-wave-current coupling effect on the sea， a 10MW-level super-large offshore wind turbine in Wailuo Wind Farm， Guangdong is chosen as a research object and a real-time meso-scale WRF-SWAN-FVCOM （W-S-F） coupling simulation platform is constructed by using Model Coupling Toolkit （MCT）. The spatial-temporal evolution of typhoon wave-current in the offshore wind farm in the whole landing process of the super typhoon “Ramason” is analyzed. Next， wind load characteristics of wind turbines and interference effect among blade， tower and wave surface are analyzed by combining the meso micro scale nesting method. The extreme load model at typical positions of offshore wind turbine under extreme wind conditions is proposed. Results demonstrate that the constructed meso-scale W-S-F coupling platform can simulate interactions among typhoon，wave and current accurately. Wind loads on the tower are mainly transversal in the section within the blade interference， and are downward in the section within wave interference. Moreover， strong pulsation features are observed near the low-altitude wave surface. Blade at position A is the safest， while blade at position B is the most dangerous. T4 is the most adverse phase for single pile foundation strength design of the offshore wind turbine. At T4 phase， the maximum base shear reaches the 7.68×106 magnitude and the maximum base bending moment reaches the 5.2×108 magnitude.