Hunting motion is an inherent property of rail vehicles. With the development of high-speed railways in China， the stability problem of high-speed EMUs is becoming more and more prominent. The anti-yaw damper has an important impact on the stability of the vehicle and can be optimized to improve the operational performance of high-speed EMUs. The paper firstly establishes the vehicle dynamics model of high-speed EMUs， and selects the anti-yaw damper parameters by using Super Latin sampling.Then， the paper uses the Kriging surrogate model （KSM） for dynamic response analysis， and utilizes the nondominated sorting genetic algorithms Ⅱ（NSGA-Ⅱ） to optimize the anti-yaw damper parameters. The dynamic performance of high-speed EMUs is compared before and after parameters optimization. The results show that the optimized parameters increase the critical speed of XP55 standard wheel profile by 15.28%， which reach 463.8 km/h and the critical speed of XP55 worn wheel profile increased by 13.71%. At the same time， the optimized parameters for the ride and comfort index of the carbody are further improved， and the lateral force of the wheel axle is reduced. At the same time， the optimized parameters reduce the lateral acceleration amplitude of the carbody and bogie for the new and worn wheel profiles， and suppress the vehicle lateral vibration. Finally， the effect of antiyaw damper parameters on the contact point location and wheel wear index was analyzed. The optimized parameters reduced the lateral movement of wheel contact point， the wear index of the XP55 standard wheel profile is reduced by 14.65% at a speed of 250 km/h， and the wear index of the XP55 worn wheel profile is reduced by 15.8%. Therefore， the optimized anti-yaw damper parameters can effectively improve the stability and running performance