Cumulative pitch error is a common form of manufacturing error in gear transmission systems. Considering the cumula? tive pitch errors， a load distribution model is established based on the loaded tooth contact analysis method. The mesh stiffness and non-loaded transmission error obtained from the load distribution model are imported into the dynamic model of the geared rotor system to acquire the vibration responses. Based on the dynamic load distribution and Archard’s wear theory， a wear prediction model of gear pairs is established. In order to verify the proposed model， the simulated results are compared with the experimental results in a published literature. On the basis of the proposed model， the effects of the cumulative pitch errors on meshing character? istics， response characteristics and wear distribution are discussed. It is found that cumulative pitch errors will lead to the non-uni? form load distribution and wear distribution among gear teeth， introducing the shaft frequency， hunting tooth frequency and assem? bly phase frequency into the vibration responses. Mild wear is beneficial to relieve the non-uniform wear among gear teeth. Howev? er， the severe wear will deteriorate the contact state， leading to violent vibration. The wear non-uniformity coefficient can be re? duced by 30% after adopting the hunting tooth design. The proposed model can provide theoretical guidance for the gear wear mechanism and the design of gear parameters.